Quinolines and derivatives
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Filtered Search Results
Apexbio Technology LLC HyperTrap Q FF Column 5x1ml
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The HyperTrap Q FF Column is not a small molecule but a chromatography medium designed for the purification of biomolecules particularly proteins and nucleic acids It operates via strong anion exchange chromatography utilizing quaternary ammonium functional groups immobilized on a Fast Flow resin matrix to selectively bind negatively charged molecules under defined buffer conditions This allows for efficient separation and recovery of target biomolecules from complex mixtures The HyperTrap Q FF Column is applied in research settings for desalting buffer exchange and isolation of nucleic acids or proteins supporting downstream analyses and preparative workflows in the biomedical field
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Apexbio Technology LLC Methscopolamine 155-41-9 200mg
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Methscopolamine is a small-molecule antagonist targeting muscarinic acetylcholine receptors It is designed to inhibit these receptors thereby reducing acetylcholine-mediated signaling and regulating gastrointestinal secretions and motility Methscopolamine exerts its biological activity primarily through antagonism of muscarinic cholinergic receptors Based on these pharmacological properties methscopolamine holds research potential in studying muscarinic receptor-mediated physiological processes particularly gastrointestinal functions and secretory mechanisms and in experimental models evaluating peripheral cholinergic receptor contributions to gastrointestinal disorders
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Apexbio Technology LLC SCH772984 TFA 942183-80-4 (free base) 200mg
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SCH772984 TFA is a small-molecule inhibitor targeting extracellular signal-regulated kinase 1/2 (ERK1/2) It is designed to inhibit ERK catalytic activity thereby blocking phosphorylation of downstream substrates and regulating the RAS-RAF-MEK-ERK signaling pathway SCH772984 TFA exerts its biological activity primarily through direct interaction with ERK1/2 acting as an ATP-competitive inhibitor Based on these pharmacological properties SCH772984 TFA holds research potential in studies examining ERK signaling s role in oncogenic pathway activation tumor cell growth survival mechanisms and resistance phenomena in various cancer models
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000586088 TRICLABENDAZOLE 200MG
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eMolecules 6-FLUORO-2-METHYLQUINOLINE 5G
5000215949 6-FLUORO-2-METHYLQUINOLINE 5G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000431380 Q AGAROSE 6FF 50ML
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000665353 TNF-A 31-45 HUMAN 1MG
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Medchemexpress LLC 3,5-Dicaffeoyl-epi-quinic acid | 879305-14-3 | 97.7% | 516.45 | 5 MG
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3,5-Dicaffeoyl-epi-quinic acid is a compound extracted from *Chrysanthemum morifolium*. It demonstrates significant antioxidant activities, effectively scavenging DPPH radical and superoxide anion radical with IC50s of 5.6 and 2.9 μg/mL, respectively.
- Extracted from Chrysanthemum morifolium
- Exhibits antioxidant activities
- Scavenges DPPH radical and superoxide anion radical
- IC50s of 5.6 and 2.9 μg/mL for DPPH and superoxide anion radicals
- Appears as a white to off-white solid
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Medchemexpress LLC 5-Bromoquinoline | 4964-71-0 | 208.06 | 10 G
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5-Bromoquinoline is a biochemical reagent and organic compound used in life science research and for the manufacture of substances. It is intended for laboratory use only.
- Biochemical reagent for life science research
- Used in the manufacture of substances
- Solid appearance, white to light brown color
- Purity of 98.1%
- Molecular weight of 208.06
- Stable under recommended storage conditions
- Melting point 50-52°C
- Boiling point 295.9°C
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Medchemexpress LLC Mefloquine (Standard) | 53230-10-7 | MFCD00869324 | 378.31 | 100 MG
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Mefloquine (Standard) is the analytical standard of Mefloquine, intended for research and analytical applications. It is an orally active and potent quinoline antimalarial agent and an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. This analytical standard grade compound is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Orally active and potent quinoline antimalarial agent.
- Anti-SARS-CoV-2 entry inhibitor.
- K+ channel (KvQT1/minK) antagonist.
- Used for malaria, systemic lupus erythematosus, and cancer research.
- Analytical standard grade for qualitative, quantitative, and methodological research experiments.
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Medchemexpress LLC Pyrroloquinoline quinone disodium salt | 122628-50-6 | 98.0% | 374.17 g/mol | C14H4N2Na2O8 | 50 MG
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Pyrroloquinoline quinone disodium salt is the disodium salt form of the redox cofactor PQQ supplied for research and analytical applications. The material is a pink to red solid used in studies of metabolism, oxidative stress, and cellular signaling. It is provided as a small powdered reagent with recommended sealed storage to preserve stability.
- Redox co-factor used in metabolic and oxidative stress research.
- High purity suitable for analytical and biological applications.
- Pink to red solid that is easy to weigh and handle.
- Stable when stored sealed and protected from moisture.
- Available in small powder pack sizes for laboratory use.
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Cambridge Isotope Laboratories 1 2 3 9-TetraCDF (unlabeled) 25 ng/mL in nonane 0 2 mL
1 2 3 9-TetraCDF (unlabeled) 25 ng/mL in nonane 0 2 mL
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000430687 ACRIDINE ORANGE 10-N 10MM 1ML
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Medchemexpress LLC Benzamide, 5-(3-azetidinylamino)-N-[(1R)-1-[3-[5-[[[(1S,3R)-3-hydroxycyclopentyl)amino]methyl]-2- | 2817811-16-6 | C29H36N4O2S | 200 MG
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XR8-89 is a potent papain-like protease (PLpro) inhibitor with an IC50 value of 0.1 μM. This compound induces conformational changes in SARS-CoV-2 papain-like protease, effectively inhibiting SARS-CoV-2 replication, making it suitable for research applications.
- Potent papain-like protease (PLpro) inhibitor
- IC50 value of 0.1 μM against papain-like protease
- Induces conformational changes in SARS-CoV-2 papain-like protease
- Inhibits SARS-CoV-2 replication
- For SARS-CoV-2 research use
- Purity of 97.13%
- Appears as a light yellow to yellow solid
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Medchemexpress LLC Zorifertinib | 1626387-80-1 | 99.4% | 459.90 | 200MG
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Zorifertinib (AZD3759) is a potent, orally active, and BBB-penetrant EGFR inhibitor. Its IC50s are 0.3, 0.2, and 0.2 nM for EGFR wt, EGFR L858R, and EGFR exon 19Del, respectively, at Km ATP concentrations. This compound induces cancer cell apoptosis and exhibits antitumor activity, making it suitable for research in NSCLC, HCC, and similar conditions.
- Potent EGFR inhibitor
- Orally active
- BBB-penetrant
- Induces cancer cell apoptosis
- Exhibits antitumor activity
- Applicable for NSCLC, HCC, and other research areas
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